Adverse effects of Hormone Imbalance:


  There is a growing concern of hormone imbalance with the use of opioids (Pain Pills).

 Table 1 above, lists the most common symptoms of hormone imbalances. Most of us may have no symptoms while others will suffer from significant changes. Most notable are loss of sexual drive, erectile dysfunction, loss of muscle mass & strength and depression.


  For example; Opiate use in Pain Management will decrease your gonadal sex hormones, growth hormone, cortisol, and dehydroepiandrosterone sulfate (DHEA-S) levels.  Opiates blunt the cortisol response to corticotropin, a hormone in your brain that responds to stress. This abnormal response decreases your ability to cope with daily stress and increases in pain levels. This vicious cycle increases depression and has a negative effect on your Quality of Life.
   While the clinical significance of decreased growth hormone and cortisol levels remain speculative, decreased sex hormones with lack of sexual drive and performance are well documented. See Table 2.

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 Hormone Levels Decrease with the use of Medications for pain relief.

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Hormone level decline after only 4 weeks of pain medication use. Low Testosterone is the major cause of Sexual Dysfunction in most Men and Women.

Table 1

  Before                       After

Conclusion:

  The prescribed use of medications to control pain are not without consequences. Research has implied short term use of only 3-4 weeks of medication may have far reaching negative effects. To reduce your chance of  developing these effects, only use medication at the lowest dosage and only when needed.

Immediate release medications are preferred over extended release medications.  Your physician must be aware of the various challenges associated with medications used for pain control.  Patients are advised to discuss symptoms outlined in table 1 & 2 if and when they occur.

Blood test to determine your hormone levels are obtained via a simple blood draw. 

Low "T" symptoms or low testosterone can be treated effectively with a variety of FDA approved medications and supplements. 


   Dr. John Girard MD is a Diplomat of The American Anti-Aging Society with Advanced Hormone Training. When requested he will order the appropriate testing and hormone replacements.

Careful adjustments will be required based on your response and repeated blood levels.

With the advances in modern medicine we no longer accept your symptoms as being part of the aging process.


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